GATA5 Antikörper (AA 161-260) (Alexa Fluor 350)

Produktnummer ABIN898481

Produktdetails anti-GATA5 Antikörper (Alexa Fluor 350)

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Bindungsspezifität: AA 161-260

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA5 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GATA-5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GATA5

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Andere Bezeichnung: Gata5 (GATA5 Produkte)

Synonyme: GATAS antikoerper, bB379O24.1 antikoerper, GATA-5 antikoerper, GATA5 antikoerper, xGATA5 antikoerper, xGATA-5 antikoerper, xGATA5a antikoerper, xGATA5b antikoerper, xGATA-5a antikoerper, xGATA-5b antikoerper, bb379o24.1 antikoerper, gata-4a antikoerper, gata-5a antikoerper, gata5 antikoerper, gata-5b antikoerper, cb634 antikoerper, fau/gata5 antikoerper, gta5 antikoerper, GATA binding protein 5 antikoerper, GATA binding protein 5 S homeolog antikoerper, GATA binding protein 5 L homeolog antikoerper, GATA5 antikoerper, Gata5 antikoerper, gata5 antikoerper, gata5.S antikoerper, gata5.L antikoerper

Hintergrund:

Synonyms: GATA binding protein 5, GATA-binding factor 5, GATA5, GATA-5, GATA5_HUMAN, Transcription factor GATA-5.

Background: Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.

Gen-ID: 140628