ESR2 Antikörper (AA 50-100) (Alexa Fluor 350)

Produktnummer ABIN895615

Produktdetails anti-ESR2 Antikörper (Alexa Fluor 350)

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Bindungsspezifität: AA 50-100

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESR2 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ER-Beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Andere Bezeichnung: Estrogen receptor beta (ESR2 Produkte)

Synonyme: ER-BETA antikoerper, ESR-BETA antikoerper, ESRB antikoerper, ESTRB antikoerper, Erb antikoerper, NR3A2 antikoerper, ER[b]1 antikoerper, zfER-beta1 antikoerper, zfER[b]1 antikoerper, erb2 antikoerper, CERB antikoerper, ERB antikoerper, erb antikoerper, esrb antikoerper, estrb antikoerper, nr3a2 antikoerper, ERbeta antikoerper, er-beta antikoerper, esr-beta antikoerper, ESR2 antikoerper, ERBETA antikoerper, er antikoerper, ER-beta antikoerper, ER[b] antikoerper, Estrb antikoerper, ER[b]2 antikoerper, ER[b]a antikoerper, zfER[b]2 antikoerper, zfER-beta2 antikoerper, Erb2 antikoerper, esr2 antikoerper, erbeta antikoerper, Esr2 antikoerper, ERBeta2 antikoerper, estrogen receptor 2 antikoerper, estrogen receptor 2b antikoerper, estrogen receptor beta 2 antikoerper, estrogen receptor 2 (beta) antikoerper, estrogen receptor 2a antikoerper, estrogen receptor beta antikoerper, ESR2 antikoerper, esr2b antikoerper, erb2 antikoerper, esr2 antikoerper, Esr2 antikoerper, esr2a antikoerper, erbeta antikoerper

Hintergrund:

Synonyms: Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2, ESR2

Background: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

Gen-ID: 2100

UniProt: Q92731

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling