EMP1 Antikörper (AA 101-160) (Alexa Fluor 350)

Produktnummer ABIN895261

Produktdetails anti-EMP1 Antikörper

Target: EMP1 (Epithelial Membrane Protein 1 (EMP1))

Bindungsspezifität: AA 101-160

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EMP1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Emp1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu EMP1

Target: EMP1 (Epithelial Membrane Protein 1 (EMP1))

Andere Bezeichnung: EMP1 (EMP1 Produkte)

Synonyme: MGC84779 antikoerper, EMP1 antikoerper, si:ch73-90k17.2 antikoerper, CL-20 antikoerper, EMP-1 antikoerper, TMP antikoerper, I-8-09 antikoerper, ENP1MR antikoerper, epithelial membrane protein 1 antikoerper, epithelial membrane protein 1 L homeolog antikoerper, EMP1 antikoerper, emp1.L antikoerper, emp1 antikoerper, Emp1 antikoerper

Hintergrund:

Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.

Subcellular location: Cell membrane

Synonyms: TMP, I-8-9, Epithelial membrane protein 1, EMP-1, Tumor-associated membrane protein, Emp1

Gen-ID: 13730

UniProt: P47801