DUSP26 Antikörper (AA 144-211) (Alexa Fluor 350)

Produktnummer ABIN894579

Produktdetails anti-DUSP26 Antikörper (Alexa Fluor 350)

Target: DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

Bindungsspezifität: AA 144-211

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP26 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DUSP26/MKP8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DUSP26

Target: DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

Andere Bezeichnung: DUSP26 (DUSP26 Produkte)

Synonyme: DUSP24 antikoerper, LDP-4 antikoerper, MKP8 antikoerper, NATA1 antikoerper, SKRP3 antikoerper, 2310043K02Rik antikoerper, Skrp3 antikoerper, RGD1310090 antikoerper, dual specificity phosphatase 26 antikoerper, dual specificity phosphatase 26 (putative) antikoerper, DUSP26 antikoerper, Dusp26 antikoerper

Hintergrund:

Synonyms: DSP-4, Dual specicity phosphatase 26 putative, Dual specicity phosphatase 26, Dual specicity phosphatase SKRP3, Dual specicity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specicity phosphatase 4, Low-molecular-mass dual-specicity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplied gene in thyroid anaplastic cancer, SKRP3.

Background: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).Tissue specificity:Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.