COMMD1 Antikörper (AA 95-190) (Alexa Fluor 488)

Produktnummer ABIN891768

Produktdetails anti-COMMD1 Antikörper (Alexa Fluor 488)

Target: COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

Bindungsspezifität: AA 95-190

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COMMD1 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COMMD1/MURR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu COMMD1

Target: COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

Andere Bezeichnung: COMMD1 (COMMD1 Produkte)

Synonyme: C2orf5 antikoerper, MURR1 antikoerper, murr1 antikoerper, commd1 antikoerper, si:ch211-213b8.2 antikoerper, DDBDRAFT_0184206 antikoerper, DDBDRAFT_0266452 antikoerper, DDB_0184206 antikoerper, DDB_0266452 antikoerper, COMMD1 antikoerper, MGC114682 antikoerper, AI256843 antikoerper, Murr1 antikoerper, U2/Mu antikoerper, copper metabolism domain containing 1 antikoerper, copper metabolism (Murr1) domain containing 1 antikoerper, COMM domain-containing protein 1 antikoerper, copper metabolism domain containing 1 L homeolog antikoerper, COMM domain containing 1 antikoerper, COMMD1 antikoerper, commd1 antikoerper, comd1 antikoerper, Commd1 antikoerper, commd1.L antikoerper

Hintergrund:

Synonyms: C2orf5, COMD1, COMD1_HUMAN, COMM domain-containing protein 1, COMMD1, copper metabolism domain containing 1, MGC27155, MURR1, Protein Murr1.

Background: Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.

Gen-ID: 150684

Pathways: Transition Metal Ion Homeostasis