CLEC5A Antikörper (AA 101-190) (Alexa Fluor 555)

Produktnummer ABIN891261

Produktdetails anti-CLEC5A Antikörper (Alexa Fluor 555)

Target: CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))

Bindungsspezifität: AA 101-190

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLEC5A Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CLEC5A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CLEC5A

Target: CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))

Andere Bezeichnung: CLEC5A (CLEC5A Produkte)

Synonyme: CLECSF5 antikoerper, MDL-1 antikoerper, MDL1 antikoerper, Clecsf5 antikoerper, Ly100 antikoerper, Mdl1 antikoerper, C-type lectin domain containing 5A antikoerper, C-type lectin domain family 5, member a antikoerper, CLEC5A antikoerper, Clec5a antikoerper

Hintergrund:

Synonyms: Mdl1, Ly100, MDL-1, Clecsf5, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, Clec5a

Background: Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release.

Gen-ID: 23845

UniProt: Q9R007