CITED1 Antikörper (Alexa Fluor 350)

Produktnummer ABIN890777

Produktdetails anti-CITED1 Antikörper

Target: CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CITED1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CITED1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu CITED1

Target: CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))

Andere Bezeichnung: Cited1 (CITED1 Produkte)

Synonyme: cited1 antikoerper, fi05d05 antikoerper, CITED1 antikoerper, MSG1 antikoerper, AI316840 antikoerper, AU019144 antikoerper, Msg1 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 antikoerper, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 antikoerper, similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) antikoerper, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 antikoerper, cited1 antikoerper, CITED1 antikoerper, Cited1 antikoerper

Hintergrund:

Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.

Subcellular location: Cytoplasm, Nucleus

Synonyms: MSG1, Cbp/p300-interacting transactivator 1, Melanocyte-specific protein 1, CITED1

Gen-ID: 4435

UniProt: Q99966