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CD4 Antikörper (AA 385-457) (Alexa Fluor 555)

Name: CD4 Antikörper (AA 385-457) (Alexa Fluor 555)
SKU: ABIN889094
Price: 470.46 EUR
Availability: InStock

CD4 Reaktivität: Human, Maus, Ratte, Huhn, Schwein FACS, WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 555

Paraformaldehyde-fixed, paraffin embedded rat kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with CD4 Polyclonal Antibody, AF555 conjugated (bs-0647R-A555) at 1:200 at 4°C for 90 minutes and DAPI staining of the nuclei. (CD4 Antikörper (AA 385-457) (Alexa Fluor 555))

IF (p)

1 image

Produktnummer ABIN889094

Datenblatt (PDF)

Target Alle CD4 Antikörper anzeigen

CD4
Bindungsspezifität
31

16

16

16

15

9

7

6

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 385-457
Reaktivität
378

221

119

37

23

22

20

19

15

11

10

10

8

7

7

6

6

6

6

2

2

2

1

1

1

1
Human, Maus, Ratte, Huhn, Schwein
Wirt
361

145

132

4

2

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
502

137

3
Polyklonal
Konjugat
203

69

57

51

32

15

14

14

12

11

10

9

9

8

7

7

5

5

5

5

5

5

5

5

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
Dieser CD4 Antikörper ist konjugiert mit Alexa Fluor 555
Applikation
509

204

113

109

86

80

78

41

39

38

33

25

17

10

9

8

8

7

6

6

6

5

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität

Huhn, Human, Maus, Schwein, Ratte

Homologie

Dog,Cow,Sheep,Guinea Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from Human CD4 (cytoplasmic domain)

Isotyp

IgG

Top Product

Discover our top product CD4 Primärantikörper
anti-CD4 (CD4) (AA 385-457) antibody
CD4 Reaktivität: Human, Maus, Ratte, Huhn, Schwein FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 Reaktivität: Human, Maus, Ratte, Huhn, Affe, Schwein, Hund, Cat, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege, Pferd, Hamster, Esel, Avian WB Wirt: Ziege Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
CD4 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody
CD4 Reaktivität: Human FACS, WB, CyTOF Wirt: Maus Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) (AA 300-400) antibody
CD4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 Reaktivität: Maus FACS, IP, IHC (fro), ICC, Func Wirt: Ratte Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 FITC

anti-CD4 (CD4) (AA 301-400) antibody
CD4 Reaktivität: Human, Maus, Ratte FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 PE

anti-CD4 (CD4) antibody (PE)
CD4 Reaktivität: Ratte FACS Wirt: Maus Monoclonal OX-35 PE

Applikationshinweise

FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Target

CD4

Andere Bezeichnung

CD4 (CD4 Produkte)

Synonyme

cd4 antikoerper, L3T4 antikoerper, Ly-4 antikoerper, CD4mut antikoerper, W3/25 antikoerper, p55 antikoerper, CD4 molecule antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, T-cell surface glycoprotein CD4 antikoerper, CD4 antigen antikoerper, Cd4 molecule antikoerper, CD4 antikoerper, LOC100125525 antikoerper, cd4 antikoerper, Cd4 antikoerper

Hintergrund

Synonyms: T-cell surface glycoprotein CD4, Cd4, T-cell surface antigen T4/Leu-3, W3/25 antigen
Background: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.

Gen-ID

24932

UniProt

P01730

Pathways

T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events