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Bax beta Antikörper (AA 141-218) (Cy5.5)

BAX beta Reaktivität: Human FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN884808
  • Target Alle Bax beta (BAX beta) Produkte
    Bax beta (BAX beta) (BCL2-Associated X Protein (Isoform beta) (BAX beta))
    Bindungsspezifität
    AA 141-218
    Reaktivität
    Human
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Bax beta Antikörper ist konjugiert mit Cy5.5
    Applikation
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Bax isoform beta
    Isotyp
    IgG
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Bax beta (BAX beta) (BCL2-Associated X Protein (Isoform beta) (BAX beta))
    Abstract
    BAX beta Produkte
    Hintergrund

    Synonyms: Apoptosis regulator Bax cytoplasmic isoform beta, BAX, Bax B, Bax beta, BaxB, BCL2 associated X protein, BCL2 associated X protein isoform beta.

    Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].

    Gen-ID
    581
    UniProt
    Q07812
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