Amylin/DAP Antikörper (Alexa Fluor 350)

Produktnummer ABIN882542

Produktdetails anti-Amylin/DAP Antikörper (Alexa Fluor 350)

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Amylin/DAP Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Amylin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Amylin/DAP

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Andere Bezeichnung: Amylin (IAPP Produkte)

Synonyme: DAP antikoerper, IAP antikoerper, LOC100230121 antikoerper, Amylin antikoerper, islet amyloid polypeptide antikoerper, IAPP antikoerper, Iapp antikoerper

Hintergrund:

Synonyms: Islet amyloid polypeptide, IAPP, DAP, Diabetes associated peptide, IAP, Insulinoma amyloid peptide.

Background: Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Gen-ID: 3375

Pathways: Hormone Activity, Feeding Behaviour