LLGL1 + LLGL2 (pSer650), (pSer654) Antikörper (Alexa Fluor 350)
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- Target
- LLGL1 + LLGL2
- Bindungsspezifität
- pSer650, pSer654
- Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Alexa Fluor 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
- Isotyp
- IgG
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- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- LLGL1 + LLGL2
- Andere Bezeichnung
- LLGL1 + LLGL2+
- Hintergrund
-
Synonyms: LLGL1 + LLGL2 phospho S650 + S654, LLGL1 + LLGL2 phospho Ser650 + Ser654, p-LLGL1 + p-LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650 + Ser654, p-LLGL1/LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650/654, DLG4, HGL, HUGL, HUGL1, lethal giant larvae homolog 1, lethal giant larvae homolog 2, Lethal2 giant larvae protein homolog 1, Lethal2 giant larvae protein homolog 2, LGL2, LLGL, L2GL1_HUMAN, L2GL2_HUMAN.
Background: LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
- Gen-ID
- 3996
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