DEAF1 Antikörper (AA 211-310)

Produktnummer ABIN873000

Produktdetails anti-DEAF1 Antikörper

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Bindungsspezifität: AA 211-310

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Rat,Dog,Cow,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Deformed Epidermal Autoregulatory Factor 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DEAF1

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Andere Bezeichnung: Deformed Epidermal Autoregulatory Factor 1 (DEAF1 Produkte)

Synonyme: AU042387 antikoerper, C230009B13Rik antikoerper, NUDR antikoerper, SPN antikoerper, ZMYND5 antikoerper, MYND5 antikoerper, spn antikoerper, DEAF1 antikoerper, nudr antikoerper, zmynd5 antikoerper, CG8567 antikoerper, DEAF-1 antikoerper, Deaf-1 antikoerper, Dmel\\CG8567 antikoerper, deaf1 antikoerper, l(3)76BDv antikoerper, deformed epidermal autoregulatory factor 1 (Drosophila) antikoerper, DEAF1, transcription factor antikoerper, DEAF1 transcription factor antikoerper, deformed epidermal autoregulatory factor 1 homolog antikoerper, Deformed epidermal autoregulatory factor-1 antikoerper, Deaf1 antikoerper, DEAF1 antikoerper, LOC509260 antikoerper, deaf1 antikoerper, deaf-1 antikoerper

Hintergrund:

Synonyms: DEAF1, Deformed epidermal autoregulatory factor 1 homolog, Nuclear DEA1 related transcriptional regulator, NUDR, SPN, Suppressin, Zinc finger MYND domain containing protein 5, ZMYND5, DEAF1_HUMAN.

Background: Suppressin, also known as DEAF1 is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.

Gen-ID: 10522

Pathways: Tube Formation