TWIST2 Antikörper (AA 26-30)

Produktnummer ABIN871769

Produktdetails anti-TWIST2 Antikörper

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Bindungsspezifität: AA 26-30

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWIST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous level of total Twist2 protein.

Aufreinigung: Affinity purified

Immunogen: Peptide sequence around AA 26-30 (P-K-R-F-G) derived from Human Twist2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Anwendungsinformationen

Applikationshinweise: Western blotting 1:100-1:500
Immunohistochemistry  1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu TWIST2

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Andere Bezeichnung: Twist2 (TWIST2 Produkte)

Synonyme: TWIST2 antikoerper, DERMO1 antikoerper, FFDD3 antikoerper, SETLSS antikoerper, bHLHa39 antikoerper, Dermo1 antikoerper, CDERMO-1 antikoerper, twist family bHLH transcription factor 2 antikoerper, twist basic helix-loop-helix transcription factor 2 antikoerper, TWIST2 antikoerper, Twist2 antikoerper

Hintergrund: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Gen-ID: 117581

NCBI Accession: NP_476527

UniProt: Q8WVJ9

Pathways: Chromatin Binding