JUP Antikörper (AA 726-730)
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- Target Alle JUP Antikörper anzeigen
- JUP (Junction Plakoglobin (JUP))
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Bindungsspezifität
- AA 726-730
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser JUP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- The antibody detects endogenous levels of total g-Catenin protein.
- Aufreinigung
- Affinity purified
- Immunogen
- Peptide sequence around AA 726-730 (I-D-T-Y-S) derived from Human g-Catenin Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product JUP Primärantikörper
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- Applikationshinweise
- Western blotting: 1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- JUP (Junction Plakoglobin (JUP))
- Andere Bezeichnung
- gamma-Catenin (JUP Produkte)
- Synonyme
- ARVD12 antikoerper, CTNNG antikoerper, DP3 antikoerper, DPIII antikoerper, PDGB antikoerper, PKGB antikoerper, arvd12 antikoerper, ctnng antikoerper, dp3 antikoerper, dpiii antikoerper, pdgb antikoerper, pkgb antikoerper, plak antikoerper, D930025P04Rik antikoerper, PG antikoerper, cb80 antikoerper, danPG antikoerper, fb11b06 antikoerper, jup antikoerper, wu:fb11b06 antikoerper, junction plakoglobin antikoerper, junction plakoglobin L homeolog antikoerper, Junction plakoglobin antikoerper, junction plakoglobin a antikoerper, junction plakoglobin S homeolog antikoerper, JUP antikoerper, Jup antikoerper, jup antikoerper, jup.L antikoerper, Tsp_06656 antikoerper, plak antikoerper, jupa antikoerper, jup.S antikoerper
- Hintergrund
- Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton
- Molekulargewicht
- 83 kDa
- Gen-ID
- 3728
- NCBI Accession
- NP_002221
- UniProt
- P14923
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
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