HNRNPA1 Antikörper (AA 190-194)

Produktnummer ABIN871695

Produktdetails anti-HNRNPA1 Antikörper

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Bindungsspezifität: AA 190-194

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous levels of total hnRNP A1 protein.

Aufreinigung: Affinity purified

Immunogen: Peptide sequence around AA 190-194 (S-S-S-Q-R) derived from Human hnRNP A1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu HNRNPA1

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Andere Bezeichnung: hnRNP A1 (HNRNPA1 Produkte)

Synonyme: HNRPA1 antikoerper, HNRPA1L3 antikoerper, hnRNP A1 antikoerper, hnRNP-A1 antikoerper, hnrpa1 antikoerper, TPT1P antikoerper, HNRNPA1 antikoerper, D15Ertd119e antikoerper, Hdp antikoerper, Hnrpa1 antikoerper, hnrnp-A1 antikoerper, ROA1 antikoerper, zgc:66127 antikoerper, heterogeneous nuclear ribonucleoprotein A1 antikoerper, heterogeneous nuclear ribonucleoprotein A1b antikoerper, Heterogeneous nuclear ribonucleoprotein A1 antikoerper, heterogeneous nuclear ribonucleoprotein A1 S homeolog antikoerper, ribonucleoprotein A1a antikoerper, heterogeneous nuclear ribonucleoprotein A1-like antikoerper, heterogeneous nuclear ribonucleoprotein A1a antikoerper, HNRNPA1 antikoerper, hnrnpa1b antikoerper, LOC100101226 antikoerper, roa1 antikoerper, Hnrnpa1 antikoerper, hnrnpa1.S antikoerper, hnrnpa1 antikoerper, LOC100359118 antikoerper, hnrnpa1a antikoerper

Hintergrund: Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts . hnRNP A1 regulates the alternative splicing of c-Src, c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers, knockdown of hnRNP A1 leads to apoptosis in various cancer cells . Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus . hnRNP A1 binds to cis-acting repressive sequences (CRS) of HIV-1 to influence HIV-1 production . HIV-1 enhances hnRNP A1 expression and promotes the relocalization of hnRNP A1 to the cytoplasm ,

Molekulargewicht: 39 kDa

Gen-ID: 3178

NCBI Accession: NP_002127

UniProt: P09651