IDH3B Antikörper (C-Term)

Produktnummer ABIN784283

Produktdetails anti-IDH3B Antikörper

Target: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Bindungsspezifität: AA 369-383, C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IDH3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-TTDFIKSVIG HLQTK

Spezifität: This antibody is expected to recognize isoform a (NP_008830.2) and isoform c (NP_777281.1).

Kreuzreaktivität (Details): Species reactivity (expected):Human, Rat, Canine (Dog), Pig, Cow.
Species reactivity (tested):Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_008830.2, NP_777281.1. Genename: IDH3B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IDH3B

Target: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Andere Bezeichnung: Isocitric Dehydrogenase beta / IDH3B (IDH3B Produkte)

Synonyme: H-IDHB antikoerper, RP46 antikoerper, C78231 antikoerper, zgc:86647 antikoerper, MGC79028 antikoerper, IDH1 antikoerper, IDH3 antikoerper, isocitrate dehydrogenase 3 (NAD(+)) beta antikoerper, isocitrate dehydrogenase 3 (NAD+) beta antikoerper, isocitrate dehydrogenase 3 (NAD+) beta S homeolog antikoerper, IDH3B antikoerper, Idh3B antikoerper, Idh3b antikoerper, idh3b antikoerper, idh3b.S antikoerper

Hintergrund: Defects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Belongs to the isocitrate and isopropylmalate dehydrogenases family.Synonyms: NAD(+)-specific ICDH beta, mitochondrial Isocitrate dehydrogenase [NAD] subunit beta

Gen-ID: 3420

NCBI Accession: NP_008830