NMNAT3 Antikörper (Internal Region)

Produktnummer ABIN784277

Produktdetails anti-NMNAT3 Antikörper

Target: NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))

Bindungsspezifität: Internal Region

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NMNAT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-KALGQGQSVK YLLPE

Spezifität: This antibody is expected to recognize both reported isoforms (NP_835471.1, NP_001186976.1).

Kreuzreaktivität (Details): Species reactivity (tested):Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_653116.1. Genename: Nmnat3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NMNAT3

Target: NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))

Andere Bezeichnung: NMNAT3 (NMNAT3 Produkte)

Synonyme: PNAT-3 antikoerper, PNAT3 antikoerper, 4933408N02Rik antikoerper, nicotinamide nucleotide adenylyltransferase 3 antikoerper, si:ch73-170l17.1 antikoerper, Nmnat3 antikoerper, NMNAT3 antikoerper, si:ch73-170l17.1 antikoerper

Hintergrund: NMNAT3 belongs to the eukaryotic NMN adenylyltransferase family. Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury. Expressed in lung and spleen with lower levels in placenta and kidney.Synonyms: NMN adenylyltransferase 3, Nicotinamide mononucleotide adenylyltransferase 3

Gen-ID: 74080

NCBI Accession: NP_653116