HCRTR1 Antikörper (Internal Region)

Produktnummer ABIN783920

Produktdetails anti-HCRTR1 Antikörper

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus, Hund, Schaf

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser HCRTR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-RNWKRPSDQL GD

Spezifität: This antibody detects Orexin receptor 1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog), Sheep.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001516.1. Genename: HCRTR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HCRTR1

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Andere Bezeichnung: Orexin Receptor Type 1 (HCRTR1 Produkte)

Synonyme: OX1R antikoerper, Ox1r antikoerper, Hctr1 antikoerper, HCRTR1 antikoerper, hypocretin receptor 1 antikoerper, hypocretin (orexin) receptor 1 antikoerper, HCRTR1 antikoerper, Hcrtr1 antikoerper

Hintergrund: Orexins are endogeneous peptides that activate Orexin Receptor type 1 and type 2, two closely related G-protein coupled receptors. Orexins-A and -B are hypothalamic peptides derived from a precursor called preproorexin and affect the stimulation of food intake. They act on G protein receptors named orexin receptor-1 (OX1R) and orexin receptor-2 (OX2R), respectively.timulation of these receptors by orexins causes an increase in intracellular calcium levels in hypothalamic cells in vitro. In vivo, orexins control feeding and may also be involved in modulating sleep-wake cycles and other hypothalamic functions.Synonyms: HCRTR1, Hypocretin receptor type 1, Ox1r

Gen-ID: 3061

NCBI Accession: NP_001516

Pathways: Feeding Behaviour