MMP11 Antikörper

Produktnummer ABIN783851

Produktdetails anti-MMP11 Antikörper

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide surrounding amino acid 464 of mouse MMP-11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.

Details zu MMP11

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Andere Bezeichnung: MMP-11 (MMP11 Produkte)

Synonyme: SL-3 antikoerper, ST3 antikoerper, STMY3 antikoerper, Stmy3 antikoerper, MMP-11 antikoerper, matrix metallopeptidase 11 antikoerper, matrix metallopeptidase 11 L homeolog antikoerper, stromelysin-3 antikoerper, MMP11 antikoerper, Mmp11 antikoerper, mmp11.L antikoerper, LOC103694874 antikoerper

Hintergrund: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.Synonyms: MMP11, Matrix metalloproteinase-11, SL-3, ST3, STMY3, Stromelysin-3

Gen-ID: 4320

NCBI Accession: NP_005931

UniProt: P24347