BCAS1 Antikörper (C-Term)

Produktnummer ABIN783588

Produktdetails anti-BCAS1 Antikörper

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human BCAS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu BCAS1

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Andere Bezeichnung: BCAS1 / NABC1 (BCAS1 Produkte)

Synonyme: AIBC1 antikoerper, NABC1 antikoerper, 2210416M21Rik antikoerper, 9030223A09Rik antikoerper, AI841227 antikoerper, Band83 antikoerper, Pmes-2 antikoerper, BCAS1 antikoerper, MGC152145 antikoerper, breast carcinoma amplified sequence 1 antikoerper, BCAS1 antikoerper, Bcas1 antikoerper

Hintergrund: BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein, BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.Synonyms: AIBC1, Breast carcinoma-amplified sequence 1

Gen-ID: 8537

NCBI Accession: NP_003648

UniProt: O75363