PKC alpha Antikörper

Produktnummer ABIN781344

Der Maus Monoklonal Anti-PKC alpha-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, PKC alpha in Proben von Human zu detektieren.

Kurzübersicht für PKC alpha Antikörper (ABIN781344)

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKC alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PKC alpha Antikörper

Spezifität: Cytoplasm

Aufreinigung: Protein G-Sepharose affinity purified.

Immunogen: Recombinant fragment of human PRKCA (C-terminus).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu PKC alpha

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Andere Bezeichnung: PRKCA

Hintergrund: PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Molekulargewicht: 50kDa

NCBI Accession: NM_002737

Pathways: WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling