CARM1 Antikörper (pSer228) (Cy5.5)
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- Target Alle CARM1 Antikörper anzeigen
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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Bindungsspezifität
- pSer228
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CARM1 Antikörper ist konjugiert mit Cy5.5
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human CARM1 around the phosphorylation site of Ser228
- Isotyp
- IgG
- Top Product
- Discover our top product CARM1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
- Andere Bezeichnung
- CARM1 (CARM1 Produkte)
- Synonyme
- NV18905 antikoerper, prmt4 antikoerper, PRMT4 antikoerper, Prmt4 antikoerper, si:dkey-204f11.63 antikoerper, zgc:100805 antikoerper, coactivator associated arginine methyltransferase 1 antikoerper, coactivator associated arginine methyltransferase 1 L homeolog antikoerper, coactivator-associated arginine methyltransferase 1 antikoerper, histone-arginine methyltransferase CARM1 antikoerper, CARM1 antikoerper, carm1.L antikoerper, Carm1 antikoerper, carm1 antikoerper, LOC100352221 antikoerper
- Hintergrund
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Synonyms: CARM1_HUMAN, Coactivator associated arginine methyltransferase 1, Coactivator-associated arginine methyltransferase 1, Histone arginine methyltransferase CARM 1, Histone arginine methyltransferase CARM1, Histone-arginine methyltransferase CARM1, PRMT 4, Protein arginine methyltransferase, Protein arginine N methyltransferase 4, Protein arginine N-methyltransferase 4.
Background: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
- Gen-ID
- 10498
- UniProt
- Q86X55
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
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