CTSC Antikörper (AA 365-463)

Produktnummer ABIN748898

Produktdetails anti-CTSC Antikörper

Target: CTSC (Cathepsin C (CTSC))

Bindungsspezifität: AA 365-463

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTSC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DPP-I

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CTSC

Target: CTSC (Cathepsin C (CTSC))

Andere Bezeichnung: Cathepsin C/DPP1 (CTSC Produkte)

Synonyme: CPPI antikoerper, DPP-I antikoerper, DPP1 antikoerper, DPPI antikoerper, HMS antikoerper, JP antikoerper, JPD antikoerper, PALS antikoerper, PDON1 antikoerper, PLS antikoerper, MGC69126 antikoerper, MGC107782 antikoerper, AI047818 antikoerper, CATC antikoerper, cb912 antikoerper, ik:tdsubc_1h2 antikoerper, sb:cb146 antikoerper, wu:fb34g12 antikoerper, wu:fj58d01 antikoerper, cathepsin C antikoerper, cathepsin C L homeolog antikoerper, cathepsin CPC1 antikoerper, CTSC antikoerper, ctsc.L antikoerper, ctsc antikoerper, TP03_0357 antikoerper, CMU_003360 antikoerper, CPC1 antikoerper, NAEGRDRAFT_80477 antikoerper, NAEGRDRAFT_37577 antikoerper, Ctsc antikoerper, Smp_183330 antikoerper

Hintergrund:

Synonyms: Dipeptidyl peptidase I, AI047818, CATC, Cathepsin C, Cathepsin J, CPPI, CTSC, Dipeptidyl peptidase 1, Dipeptidyl transferase, DPP I, DPPI, EC 3.4.14.1, HMS, JP, JPD, MGC126959, PALS, PLS.

Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Gen-ID: 1075