RAF1 Antikörper (pSer296) (Biotin)

Produktnummer ABIN745405

Produktdetails anti-RAF1 Antikörper (Biotin)

Target: RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))

Bindungsspezifität: pSer296

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAF1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Ser296

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu RAF1

Target: RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))

Andere Bezeichnung: c-Raf (RAF1 Produkte)

Synonyme: CRAF antikoerper, NS5 antikoerper, Raf-1 antikoerper, c-Raf antikoerper, c-raf antikoerper, craf antikoerper, raf1 antikoerper, RAF1 antikoerper, 6430402F14Rik antikoerper, AA990557 antikoerper, BB129353 antikoerper, Craf1 antikoerper, D830050J10Rik antikoerper, v-Raf antikoerper, raf antikoerper, cRaf antikoerper, Raf-1 proto-oncogene, serine/threonine kinase antikoerper, Raf-1 proto-oncogene, serine/threonine kinase a antikoerper, v-raf-leukemia viral oncogene 1 antikoerper, Raf-1 proto-oncogene, serine/threonine kinase S homeolog antikoerper, RAF1 antikoerper, Raf1 antikoerper, raf1a antikoerper, raf1 antikoerper, raf1.S antikoerper

Hintergrund:

Synonyms: RAF1phospho S296, RAF1, murine leukemia viral v-raf-1 oncogene homolog 1 3611-MSV, v-raf-1 murine leukemia viral oncogene homolog 1, cRaf, C-RAF, proto-oncogene c-RAF, 6430402F14Rik, AA990557, BB129353, c-Raf, Craf1, D830050J10Rik, MGC102375, Raf-1, Raf 1, v-Raf, c Raf, Craf 1 transforming gene, Craf1 transforming gene, EC 2.7.11.1, Murine sarcoma 3611 oncogene 1, RAF, Raf proto oncogene serine/threonine protein kinase, vraf1 murine leukemia viral oncogene homolog 1, c-Raf.

Background: The Raf family of serine/threonine specific kinases is comprised of three members (aRaf, bRaf, and cRaf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen activated protein kinase (MAPK) pathway. cRaf kinase (also known as Raf1) is a small GTPase like kinase of 73 kDa, and is a signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that once activated, phosphorylates MEK which in turn phosphorylates ERK. Raf1 is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is part of the Ras dependent signaling pathway from receptors to the nucleus.

Gen-ID: 5894

Pathways: MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling