Rekombinanter RAF1 Antikörper (AA 300-350)
Kurzübersicht für Rekombinanter RAF1 Antikörper (AA 300-350) (ABIN7795692)
Target
Alle RAF1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 300-350
-
Verwendungszweck
- Rabbit anti-RAF1/c-Raf Recombinant Monoclonal Antibody [BLR289L]
-
Aufreinigung
- Purified
-
Immunogen
- Between 300 and 350
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,IP,6 μL/mg lysate ,WB,11000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1000 μg/mL
-
Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- 2 - 8 °C
-
Haltbarkeit
- 12 months
-
-
- RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
-
Andere Bezeichnung
- RAF1/c-Raf
-
Hintergrund
- RAF1 is a mitogen activated kinase kinase kinase (MAPKKK). In response to extracellular signals, RAF1 phosphorylates the MEK1 and MEK2 MAP kinase kinases. MEK1 and MEK2 subsequently phosphorylate and activate the ERK1 and ERK2 MAP kinases to exert pleiotropic effects on cellular functions such as growth, division, differentiation, motility, and apoptosis. RAF1 associates with the Ras family of membrane GTPases and functions downstream of Ras activity.
-
Gen-ID
- 5894
-
UniProt
- P04049
-
Pathways
- MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling
Target
-