CLEC4A Antikörper (PE)

Produktnummer ABIN7506130

Produktdetails anti-CLEC4A Antikörper (PE)

Target: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLEC4A Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Verwendungszweck: Anti-Hu CD367 PE

Spezifität: The mouse monoclonal antibody 9E8 recognizes an extracellular epitope of human CD367, a type II transmembrane protein of C-lectin family, expressed mainly on antigen presenting cells.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: CD367 ectodomain fused with human Fc

Klon: 9E8

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu CLEC4A

Target: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Andere Bezeichnung: CD367 (CLEC4A Produkte)

Synonyme: CLEC4A antikoerper, CLECSF6 antikoerper, DCIR antikoerper, DDB27 antikoerper, LLIR antikoerper, Clecsf6 antikoerper, Dcir1 antikoerper, Clec4a antikoerper, zinc finger protein 705A antikoerper, C-type lectin domain family 4 member A antikoerper, C-type lectin domain family 4, member A antikoerper, C-type lectin domain family 4, member a2 antikoerper, ZNF705A antikoerper, CLEC4A antikoerper, Clec4a antikoerper, Clec4a2 antikoerper

Hintergrund: C-type lectin domain family 4 member A,CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose, fucose, and weakly also to N-acetylglucosamine. It is expressed on dendritic cells, macrophages, monocytes, B cells, and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering, it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.,DCIR, CLEC4A, LLIR

Gen-ID: 50856

UniProt: Q9UMR7