TCR, V delta 2 Antikörper (PE)
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- Target
- TCR, V delta 2
- Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- PE
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Applikation
- Flow Cytometry (FACS)
- Verwendungszweck
- Anti-Hu TCR Vdelta2 PE
- Spezifität
- The mouse monoclonal antibody B6 recognizes an extracellular epitope of human TCR Vdelta2, which is expressed on the majority of gamma/delta T cells.
- Aufreinigung
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- human recombinant TCR Vdelta2
- Klon
- B6
- Isotyp
- IgG1 kappa
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anti-TCR, V delta 2 antibody
Reaktivität: Human FACS Wirt: Maus Monoclonal B6 unconjugated
anti-TCR, V delta 2 antibody (Biotin)Reaktivität: Human FACS Wirt: Maus Monoclonal B6 Biotin
anti-TCR, V delta 2 antibody (PerCP)Reaktivität: Human FACS, IF, IHC, BR, CyTOF Wirt: Maus Monoclonal B6 PerCP
anti-TCR, V delta 2 antibody (FITC)Reaktivität: Human FACS Wirt: Maus Monoclonal B6 FITC
anti-TCR, V delta 2 antibody (PE)Reaktivität: Human FACS, IF Wirt: Maus Monoclonal B6 PE
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- Applikationshinweise
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- TCR, V delta 2
- Andere Bezeichnung
- TCR Vdelta2
- Hintergrund
- TCR Vdelta2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56.,TCRVD2
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