CLEC4D Antikörper (APC)

Produktnummer ABIN7505925

Produktdetails anti-CLEC4D Antikörper (APC)

Target: CLEC4D (C-Type Lectin Domain Family 4, Member D (CLEC4D))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLEC4D Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Verwendungszweck: Anti-Hu CD368 APC

Spezifität: The mouse monoclonal antibody 9B9 recognizes an extracellular epitope of CD368, a type II transmembrane protein of C lectin family, expressed mainly on monocytes and neutrophils.

Aufreinigung: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: CD368 ectodomain fused with human Fc

Klon: 9B9

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu CLEC4D

Target: CLEC4D (C-Type Lectin Domain Family 4, Member D (CLEC4D))

Andere Bezeichnung: CD368 (CLEC4D Produkte)

Synonyme: CLEC4D antikoerper, CLEC-6 antikoerper, CLEC6 antikoerper, CLECSF8 antikoerper, MCL antikoerper, MPCL antikoerper, Clecsf8 antikoerper, Mpcl antikoerper, mcl antikoerper, Mcl antikoerper, C-type lectin domain family 4 member D antikoerper, C-type lectin domain family 4, member d antikoerper, C-type lectin domain family 4, member D antikoerper, CLEC4D antikoerper, LOC611536 antikoerper, Clec4d antikoerper

Hintergrund: C-type lectin domain family 4 member D,CD368 is an approximately 25-30 kDa C-type lectin, which serves as one of pattern recognition receptors of the innate immune system. It recognizes pathogen-associated molecular patterns of bacteria and fungi, such as alpha-mannans or trehalose 6,6´-dimycolate, and transfers the signal downstream using associated Fc receptor gamma chain. CD368 is expressed on neutrophils, monocytes, and on some populations of blood dendritic cells, but it decreases during differentiation of monocytes into dendritic cells or macrophages. Increased expression can be induced by IFN-gamma, TNF-alpha, IL-6, and IL-10. CD368 triggering leads to driving of antigen-presenting cells maturation and to promotion of T cell differentiation into Th1 and Th17.,CLEC6, CLEC4D, dectin 3, MCL, MPCL

Gen-ID: 338339

UniProt: Q8WXI8