FCER2 Antikörper (AA 48-321)

Produktnummer ABIN7477405

Produktdetails anti-FCER2 Antikörper

Target: FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

Bindungsspezifität: AA 48-321

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FCER2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Immunogen: Recombinant fragment (around aa 48-321) of human FCER2/CD23 protein (exact sequence is proprietary)

Klon: MSVA-023M

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200

Kommentare:

Positive Control: Tonsil: The follicular dendritic cells of the germinal centres should show a strong CD23 immunostaining while the majority of lymphocytes in the mantle zone of the follicles should show an at least weak staining.

Negative Control: Tonsil: The squamous epithelial cells and T-cells in the interfollicular T-zones should not show any CD23 immunostaining.

Protokoll: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer's directions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non- hazardous.

Details zu FCER2

Target: FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

Andere Bezeichnung: CD23 (FCER2 Produkte)

Synonyme: BLAST-2 antikoerper, CD23 antikoerper, CD23A antikoerper, CLEC4J antikoerper, FCE2 antikoerper, IGEBF antikoerper, Fcer2a antikoerper, Fc fragment of IgE receptor II antikoerper, FCER2 antikoerper, Fcer2 antikoerper

Hintergrund: BLAST-2, C-type lectin domain family 4, member J, Fc fragment of IgE low affinity II receptor, Fc-epsilon-RII, FCER2, FCER2A, FceRII, IgE-binding factor (IGEBF), Immunoglobulin E receptor, low affinity II, Lymphocyte IgE receptor,CD23 antibody validated for immunohistochemistry on 76 different Normal Tissues

UniProt: P06734

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process