PSMB1 Antikörper

Produktnummer ABIN7468790

Produktdetails anti-PSMB1 Antikörper

Target: PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSMB1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.89 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PSMB1

Target: PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))

Andere Bezeichnung: proteasome subunit beta 1 (PSMB1 Produkte)

Synonyme: DDBDRAFT_0217063 antikoerper, DDBDRAFT_0232957 antikoerper, DDB_0217063 antikoerper, DDB_0232957 antikoerper, AA409053 antikoerper, C81484 antikoerper, Lmpc5 antikoerper, HC5 antikoerper, PMSB1 antikoerper, PSC5 antikoerper, wu:fc51f06 antikoerper, zgc:103665 antikoerper, proteasome subunit beta 1 antikoerper, 20S proteasome subunit beta-1 antikoerper, proteasome subunit beta type 1 antikoerper, proteasome (prosome, macropain) subunit, beta type 1 antikoerper, proteasome subunit beta 1 S homeolog antikoerper, psmb1 antikoerper, PSMB1 antikoerper, psmB1 antikoerper, LOC100286342 antikoerper, Psmb1 antikoerper, psmb1.S antikoerper

Hintergrund:

Synonyms: proteasome subunit beta 1 , HC5 , PMSB1 , PSC5

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq]

Molekulargewicht: 26 kDa

Gen-ID: 5689

UniProt: P20618

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA