ATP6V1B2 Antikörper

Produktnummer ABIN7468018

Produktdetails anti-ATP6V1B2 Antikörper

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ATP6V1B2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , mouse brain , rat brain Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ATP6V1B2

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Andere Bezeichnung: ATPase H+ transporting V1 subunit B2 (ATP6V1B2 Produkte)

Synonyme: Atp6b1b2 antikoerper, Atp6b2 antikoerper, Vatb antikoerper, vha55 antikoerper, VATB antikoerper, ATP6B1B2 antikoerper, ATP6B2 antikoerper, HO57 antikoerper, VPP3 antikoerper, Vma2 antikoerper, atp6v1bb antikoerper, fj51e01 antikoerper, vatB2 antikoerper, wu:fj51e01 antikoerper, zgc:109771 antikoerper, AI194269 antikoerper, AI790362 antikoerper, R74844 antikoerper, ATPase H+ transporting V1 subunit B2 antikoerper, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog antikoerper, ATPase, H+ transporting, lysosomal, V1 subunit B2 antikoerper, ATPase, H+ transporting, lysosomal V1 subunit B2 antikoerper, Atp6v1b2 antikoerper, atp6v1b2.S antikoerper, ATP6V1B2 antikoerper, atp6v1b2 antikoerper

Hintergrund:

Synonyms: ATPase H+ transporting V1 subunit B2 , ATP6B1B2 , ATP6B2 , DOOD , HO57 , VATB , VPP3 , Vma2 , ZLS2

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]

Molekulargewicht: 57 kDa

Gen-ID: 526

UniProt: P21281

Pathways: Transition Metal Ion Homeostasis, Proton Transport