ATP6V1B1 Antikörper

Produktnummer ABIN7468017

Produktdetails anti-ATP6V1B1 Antikörper

Target: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human V-ATPase B1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.42 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ATP6V1B1

Target: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Andere Bezeichnung: ATPase H+ transporting V1 subunit B1 (ATP6V1B1 Produkte)

Synonyme: ATP6B1 antikoerper, RTA1B antikoerper, VATB antikoerper, VMA2 antikoerper, VPP3 antikoerper, AW208839 antikoerper, Atp6b1 antikoerper, D630003L15 antikoerper, D630030L16Rik antikoerper, D630039P21Rik antikoerper, Vpp-3 antikoerper, Vpp3 antikoerper, ATPase H+ transporting V1 subunit B1 antikoerper, ATPase, H+ transporting, lysosomal V1 subunit B1 antikoerper, ATP6V1B1 antikoerper, Atp6v1b1 antikoerper

Hintergrund:

Synonyms: ATPase H+ transporting V1 subunit B1 , ATP6B1 , RTA1B , VATB , VMA2 , VPP3

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq]

Molekulargewicht: 57 kDa

Gen-ID: 525

UniProt: P15313

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport