KCNN4 Antikörper (AA 325-427)

Produktnummer ABIN719786

Produktdetails anti-KCNN4 Antikörper

Target: KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))

Bindungsspezifität: AA 325-427

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNN4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNN4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-KCNN4 Antikörper (ABIN719786)

Lively, Lam, Wong, Schlichter: "Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels." in: Frontiers in cellular neuroscience, Vol. 12, pp. 115, (2018) (PubMed).

Zhang, Yang, Yin, Yi, Shen, Zhao, Zhu, Liu: "Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154471, (2016) (PubMed).

Details zu KCNN4

Target: KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))

Andere Bezeichnung: KCNN4 (KCNN4 Produkte)

Synonyme: KCa3.1 antikoerper, IK1 antikoerper, IKCA1 antikoerper, KCA4 antikoerper, SK4 antikoerper, hIKCa1 antikoerper, hKCa4 antikoerper, hSK4 antikoerper, rKCNN4c antikoerper, rSK4 antikoerper, SKCas antikoerper, mIKCa1 antikoerper, potassium calcium-activated channel subfamily N member 4 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 antikoerper, KCNN4 antikoerper, Kcnn4 antikoerper

Hintergrund:

Synonyms: IK1, SK4, KCA4, hSK4, IKCA1, hKCa4, KCa3.1, hIKCa1, Intermediate conductance calcium-activated potassium channel protein 4, SKCa 4, SKCa4, Putative Gardos channel, KCNN4

Background: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.

Gen-ID: 3783

UniProt: O15554