CSTF2T Antikörper (AA 566-616)
Kurzübersicht für CSTF2T Antikörper (AA 566-616) (ABIN7454755)
Target
Alle CSTF2T Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 566-616
-
Verwendungszweck
- Rabbit anti-CSTF2T/TauCSTF64 Antibody, Affinity Purified
-
Homologie
- Mouse
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 566 and 616
-
Isotyp
- IgG
-
-
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 1-616) antibody
CSTF2T Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (N-Term) antibodyCSTF2T Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 420-560) antibodyCSTF2T Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) antibodyCSTF2T Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (C-Term) antibodyCSTF2T Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 566-616) antibodyCSTF2T Reaktivität: Human IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (Internal Region) antibodyCSTF2T Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 521-570) antibodyCSTF2T Reaktivität: Human, Ratte, Pferd, Rind (Kuh), Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 460-509) antibodyCSTF2T Reaktivität: Human, Pferd, Hund, Rind (Kuh), Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (C-Term) antibodyCSTF2T Reaktivität: Human, Maus, Ratte, Pferd, Meerschweinchen, Hund, Rind (Kuh), Kaninchen WB, IF Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
-
Andere Bezeichnung
- CSTF2T/TauCSTF64
-
Hintergrund
- Background: CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously, however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
-
Gen-ID
- 23283
-
NCBI Accession
- NP_056050
-
UniProt
- Q9H0L4
Target
-
