GTF3C2 Antikörper (AA 75-125)

Produktnummer ABIN7454394

Produktdetails anti-GTF3C2 Antikörper

Target: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Bindungsspezifität: AA 75-125

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF3C2 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-GTF3C2/TFIIIC110 Antibody, Affinity Purified

Homologie: Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 75 and 125

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu GTF3C2

Target: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Andere Bezeichnung: GTF3C2/TFIIIC110 (GTF3C2 Produkte)

Synonyme: TFIIIC110 antikoerper, GTF3C2 antikoerper, MGC155253 antikoerper, TF3C-beta antikoerper, DKFZp469M0113 antikoerper, 1300004C11Rik antikoerper, 2610510G03Rik antikoerper, AI225816 antikoerper, AU041069 antikoerper, mKIAA0011 antikoerper, TFIIIC-BETA antikoerper, general transcription factor IIIC subunit 2 antikoerper, general transcription factor IIIC, polypeptide 2, beta antikoerper, Gtf3c2 antikoerper, GTF3C2 antikoerper

Hintergrund: Background: General transcription factor 3C polypeptide 2 (GTF3C2/TFIIIC110) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C2/TFIIIC110 to the TFIIIC complex has not been fully determined. TFIIIC that is not associated with GTF3C2/TFIIIC110 has been purified, and it has been proposed that GTF3C2/TFIIIC110 functions to activate the TFIIIC complex for RNA polymerase III transcription. Recent studies argue against this model of GTF3C2/TFIIIC110 function.

Gen-ID: 2976

NCBI Accession: NP_001512

UniProt: Q8WUA4