SF3B2 Antikörper (AA 825-872)

Produktnummer ABIN7453784

Produktdetails anti-SF3B2 Antikörper

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Bindungsspezifität: AA 825-872

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-SF3b145/SAP145 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 825 and 872

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SF3B2

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Andere Bezeichnung: SF3b145/SAP145 (SF3B2 Produkte)

Synonyme: 145kDa antikoerper, 2610311M13Rik antikoerper, 2810441F20Rik antikoerper, B230398H18Rik antikoerper, SAP145 antikoerper, SF3b1 antikoerper, SF3b145 antikoerper, SF3b150 antikoerper, SF3B2 antikoerper, cus1 antikoerper, sap145 antikoerper, sf3b145 antikoerper, sf3b150 antikoerper, Cus1 antikoerper, SF3B145 antikoerper, splicing factor 3b, subunit 2 antikoerper, splicing factor 3b subunit 2 antikoerper, splicing factor 3B subunit 2 antikoerper, splicing factor 3b subunit 2 L homeolog antikoerper, Sf3b2 antikoerper, SF3B2 antikoerper, LOC714747 antikoerper, sf3b2.L antikoerper, sf3b2 antikoerper

Hintergrund: Background: SF3b145/SAP145 is a 145 kDa subunit of the splicing factor 3B (SF3B) protein complex. The SF3B complex is composed of at least 8 subunits (SF3B1 through SF3B8). SF3A along with SF3B and a 12S RNA unit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. In this complex SF3B2 interacts directly with SF3B4 and associates with the pre-mRNA upstream of the branch site at the anchoring site. SF3A and SF3B may play a role in anchoring the U2 snRNP to the pre-mRNA upstream of the intron's branch site.

Gen-ID: 10992

UniProt: Q13435