PSMB2 Antikörper (AA 151-201)

Produktnummer ABIN7453444

Produktdetails anti-PSMB2 Antikörper

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Bindungsspezifität: AA 151-201

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-PSMB2 Antibody, Affinity Purified

Homologie: Bovine

Aufreinigung: Affinity Purified

Immunogen: Between AA 151 and 201

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PSMB2

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Andere Bezeichnung: PSMB2 (PSMB2 Produkte)

Synonyme: HC7-I antikoerper, 19.m02268 antikoerper, DDBDRAFT_0190287 antikoerper, DDBDRAFT_0232958 antikoerper, DDB_0190287 antikoerper, DDB_0232958 antikoerper, Psmb2 antikoerper, ACYPI004276 antikoerper, AU045357 antikoerper, AW108089 antikoerper, C7-I antikoerper, D4Wsu33e antikoerper, zgc:92282 antikoerper, proteasome subunit beta 2 antikoerper, proteasome subunit beta type 2 antikoerper, proteasome beta 2 subunit antikoerper, putative proteasome beta 2 subunit antikoerper, 20S proteasome subunit beta-2 antikoerper, proteasome (prosome, macropain) subunit, beta type 2 antikoerper, proteasome subunit beta 2 L homeolog antikoerper, PSMB2 antikoerper, CNC04990 antikoerper, Tc00.1047053510287.30 antikoerper, Tc00.1047053503891.100 antikoerper, Tc00.1047053508461.430 antikoerper, LBRM_34_3820 antikoerper, LBRM_35_0400 antikoerper, BBOV_I004450 antikoerper, LMJF_36_0320 antikoerper, psmB2 antikoerper, Psmb2 antikoerper, psmb2 antikoerper, psmb2.L antikoerper

Hintergrund: Background: Proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2) is a component of the proteasome, a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA2 is a member of the peptidase T1A family, that is a 20S core alpha subunit [taken from NCBI Entrez Gene (Gene ID: 5683)].

Gen-ID: 5690

NCBI Accession: NP_002785

UniProt: P49721

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA