SPTY2D1 Antikörper (AA 75-125)
SPTY2D1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
-
- Target Alle SPTY2D1 Produkte
- SPTY2D1 (SPT2, Suppressor of Ty, Domain Containing 1 (SPTY2D1))
- Bindungsspezifität
- AA 75-125
- Reaktivität
- Human
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit anti-SPTY2D1 Antibody, Affinity Purified
- Homologie
- Mouse
- Aufreinigung
- Affinity Purified
- Immunogen
- Between AA 75 and 125
- Isotyp
- IgG
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- Applikationshinweise
-
IP: Not recommended
WB: 1:1,000 - 1:5,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
-
- Target
- SPTY2D1 (SPT2, Suppressor of Ty, Domain Containing 1 (SPTY2D1))
- Andere Bezeichnung
- SPTY2D1 (SPTY2D1 Produkte)
- Synonyme
- 5830435K17Rik antikoerper, AI852426 antikoerper, P16H6 antikoerper, SPT2 chromatin protein domain containing 1 antikoerper, SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) antikoerper, SPTY2D1 antikoerper, Spty2d1 antikoerper
- Hintergrund
- Background: SPT2, Suppressor of Ty (SPTY2D1) is a histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). It is required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). SPTY2D1 binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). It facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). SPTY2D1 modulates RNA polymerase 1-mediated transcription (By similarity) and binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026) [taken from the Universal Protein Resource (UniProt) Q68D10].
- Gen-ID
- 144108
- UniProt
- Q68D10
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