RAF1 Antikörper (AA 598-648)
Kurzübersicht für RAF1 Antikörper (AA 598-648) (ABIN7451996)
Target
Alle RAF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 598-648
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Verwendungszweck
- Rabbit anti-RAF1/c-RAF Antibody, Affinity Purified
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Homologie
- Rat,Bovine,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 598 and 648
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
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Andere Bezeichnung
- RAF1/c-RAF
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Hintergrund
- Background: RAF1 is a mitogen activated kinase kinase kinase (MAPKKK). In response to extracellular signals, RAF1 phosphorylates the MEK1 and MEK2 MAP kinase kinases. MEK1 and MEK2 subsequently phosphorylate and activate the ERK1 and ERK2 MAP kinases to exert pleiotropic effects on cellular functions such as growth, division, differentiation, motility, and apoptosis. RAF1 associates with the Ras family of membrane GTPases and functions downstream of Ras activity.
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Gen-ID
- 5894
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NCBI Accession
- NP_002871
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UniProt
- P04049
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Pathways
- MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling
Target
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