CELSR1 Antikörper (AA 2775-2825)

Produktnummer ABIN7450102

Produktdetails anti-CELSR1 Antikörper

Target: CELSR1 (Cadherin EGF LAG Seven Pass G-Type Receptor 1 (CELSR1))

Bindungsspezifität: AA 2775-2825

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELSR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-CELSR1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 2775 and 2825

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CELSR1

Target: CELSR1 (Cadherin EGF LAG Seven Pass G-Type Receptor 1 (CELSR1))

Andere Bezeichnung: CELSR1 (CELSR1 Produkte)

Synonyme: CDHF9 antikoerper, FMI2 antikoerper, HFMI2 antikoerper, ME2 antikoerper, Crsh antikoerper, Scy antikoerper, crash antikoerper, cadherin EGF LAG seven-pass G-type receptor 1 antikoerper, cadherin, EGF LAG seven-pass G-type receptor 1 antikoerper, CELSR1 antikoerper, Celsr1 antikoerper

Hintergrund: Background: Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins, a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions.CELSR1 is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis [taken from NCBI Entrez Gene (Gene ID: 9620)].

Gen-ID: 9620

NCBI Accession: NP_055061

UniProt: Q9NYQ6

Pathways: Tube Formation, Asymmetric Protein Localization