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CSTF2T Antikörper (AA 566-616)
CSTF2T
Reaktivität: Human
IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN7448495
Produktdetails anti-CSTF2T Antikörper
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Target
Alle CSTF2T Antikörper anzeigen
CSTF2T
(Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
Bindungsspezifität
Alle Epitope für CSTF2T Antikörper
AA 566-616
Reaktivität
Alle Reaktivitäten für CSTF2T Antikörper
Human
Wirt
Alle Wirte für CSTF2T Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CSTF2T Antikörper
Polyklonal
Konjugat
Alle Konjugate für CSTF2T Antikörper
Dieser CSTF2T Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CSTF2T Antikörper
Immunohistochemistry (IHC)
Verwendungszweck
Rabbit anti-CSTF2T/TauCSTF64 IHC Antibody, Affinity Purified
Homologie
Mouse,Rat,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Gorilla,Chimpanzee,African elephant,West Indian ocean coelacanth,White-tufted-ear marmoset,Soybean,Chinese hamster,Small-eared galago,Naked mole rat,Thirteen-lined ground squirrel,Northern white-cheeked gibbon
Aufreinigung
Affinity Purified
Immunogen
Between AA 566 and 616
Isotyp
IgG
Top Product
Discover our top product CSTF2T Primärantikörper
Alternativen
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anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (C-Term) antibody
CSTF2T
Reaktivität: Human, Maus, Ratte, Pferd, Meerschweinchen, Hund, Rind (Kuh), Kaninchen
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
1:100 - 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
250 μg/mL
Buffer
Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Haltbarkeit
12 months
Details zu CSTF2T
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Target
CSTF2T
(Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
Andere Bezeichnung
CSTF2T/TauCSTF64 (CSTF2T Produkte )
Synonyme
64kDa antikoerper, C77975 antikoerper, tCstF-64 antikoerper, tauCstF-64 antikoerper, CstF-64T antikoerper, cleavage stimulation factor, 3' pre-RNA subunit 2, tau antikoerper, cleavage stimulation factor subunit 2 tau variant antikoerper, cleavage stimulation factor subunit 2, tau variant antikoerper, Cstf2t antikoerper, CSTF2T antikoerper
Hintergrund
Background: CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously, however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
Gen-ID
23283
NCBI Accession
NP_056050
UniProt
Q9H0L4
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