SMG7 Antikörper (Internal Region)

Produktnummer ABIN7384295

Produktdetails anti-SMG7 Antikörper

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMG7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human SMG7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SMG7

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Andere Bezeichnung: SMG7 (SMG7 Produkte)

Synonyme: 9430023P16Rik antikoerper, mKIAA0250 antikoerper, C1orf16 antikoerper, EST1C antikoerper, SGA56M antikoerper, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antikoerper, SMG7, nonsense mediated mRNA decay factor antikoerper, Smg7 antikoerper, SMG7 antikoerper

Hintergrund: Breast cancer-associated antigen SGA-56M,C1orf16,EST1 like protein C,EST1 telomerase component homolog C,EST1-like protein C,EST1C,ever shorter telomeres 1C,FLJ23717,hSMG-7,nonsense mediated mRNA decay factor (C. elegans),Protein SMG7,SGA56M,SMG 7,SMG-7 homolog,Smg7,SMG7,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.SMG7 (SMG7, Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Viral mRNA Translation. GO annotations related to this gene include protein phosphatase 2A binding. An important paralog of this gene is SMG6.

Molekulargewicht:

Observed_MW: 127kDa

Calculated_MW: 127kDa

Gen-ID: 9887

UniProt: Q92540