ZGPAT Antikörper (AA 212-511)

Produktnummer ABIN7271544

Produktdetails anti-ZGPAT Antikörper

Target: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Bindungsspezifität: AA 212-511

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZGPAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: ZGPAT Rabbit pAb

Sequenz: DPDLSSLQAG SACLAKHQDG LWHAARITDV DNGYYTVKFD SLLLREAVVE GDGILPPLRT EATESDSDSD GTGDSSYARV VGSDAVDSGT CSSAFAGWEV HTRGIGSRLL TKMGYEFGKG LGRHAEGRVE PIHAVVLPRG KSLDQCVETL QKQTRVGKAG TNKPPRCRGR GARPGGRPAP RNVFDFLNEK LQGQAPGALE AGAAPAGRRS KDMYHASKSA KRALSLRLFQ TEEKIERTQR DIRSIQEALA RNAGRHSVAS AQLQEKLAGA QRQLGQLRAQ EAGLQQEQRK ADTHKKMTEF

Kreuzreaktivität: Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 212-511 of human ZGPAT (NP_852150.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZGPAT

Target: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Andere Bezeichnung: ZGPAT (ZGPAT Produkte)

Synonyme: zc3h9 antikoerper, gpatc6 antikoerper, gpatch6 antikoerper, zc3hdc9 antikoerper, GPATC6 antikoerper, GPATCH6 antikoerper, KIAA1847 antikoerper, ZC3H9 antikoerper, ZC3HDC9 antikoerper, ZIP antikoerper, 1500006I01Rik antikoerper, BC021513 antikoerper, RGD1310801 antikoerper, zgc:63730 antikoerper, zinc finger CCCH-type and G-patch domain containing antikoerper, zinc finger, CCCH-type with G-patch domain L homeolog antikoerper, zinc finger, CCCH-type with G-patch domain antikoerper, zinc finger, CCCH-type with G patch domain antikoerper, ZGPAT antikoerper, zgpat.L antikoerper, zgpat antikoerper, Zgpat antikoerper

Hintergrund: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.,ZGPAT,GPATC6,GPATCH6,KIAA1847,ZC3H9,ZC3HDC9,ZIP,Epigenetics & Nuclear Signaling,Transcription Factors,ZGPAT

Molekulargewicht: 20kDa/54kDa/55kDa/57kDa

Gen-ID: 84619

UniProt: Q8N5A5

Pathways: EGFR Signaling Pathway