Vcpip1 Antikörper (AA 923-1222)

Produktnummer ABIN7271285

Produktdetails anti-Vcpip1 Antikörper

Target: Vcpip1 (Valosin Containing Protein (p97)/p47 Complex Interacting Protein 1 (Vcpip1))

Bindungsspezifität: AA 923-1222

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vcpip1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: VCPIP1 Rabbit pAb

Sequenz: VFYSIMKKTM GMADGKHCTF PHLPGKTFVY NASEDRLELC VDAAGHFPIG PDVEDLVKEA VSQVRAEATT RSRESSPSHG LLKLGSGGVV KKKSEQLHNV TAFQGKGHSL GTASGNPHLD PRARETSVVR KHNTGTDFSN SSTKTEPSVF TASSSNSELI RIAPGVVTMR DGRQLDPDLV EAQRKKLQEM VSSIQASMDR HLRDQSTEQS PSDLPQRKTE VVSSSAKSGS LQTGLPESFP LTGGTENLNT ETTDGCVADA LGAAFATRSK AQRGNSVEEL EEMDSQDAEM TNTTEPMDHS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 923-1222 of human VCPIP1 (NP_079330.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Vcpip1

Target: Vcpip1 (Valosin Containing Protein (p97)/p47 Complex Interacting Protein 1 (Vcpip1))

Andere Bezeichnung: VCPIP1 (Vcpip1 Produkte)

Synonyme: VCPIP1 antikoerper, vcip135 antikoerper, DUBA3 antikoerper, VCIP135 antikoerper, 4932442A08 antikoerper, 5730421J18Rik antikoerper, 5730538E15Rik antikoerper, mKIAA1850 antikoerper, Vcip135 antikoerper, valosin containing protein interacting protein 1 antikoerper, valosin containing protein (p97)/p47 complex interacting protein 1 antikoerper, VCPIP1 antikoerper, vcpip1 antikoerper, Vcpip1 antikoerper

Hintergrund: Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis (By similarity. Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER (By similarity. Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity. Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.,VCPIP1,DUBA3,VCIP135,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,VCPIP1

Molekulargewicht: 134kDa

Gen-ID: 80124

UniProt: Q96JH7