TTLL12 Antikörper

Produktnummer ABIN7271032

Produktdetails anti-TTLL12 Antikörper

Target: TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTLL12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: [KO Validated] TTLL12 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Güteklasse: KO Validated

Immunogen: Recombinant protein of human TTLL12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TTLL12

Target: TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))

Andere Bezeichnung: TTLL12 (TTLL12 Produkte)

Synonyme: zgc:55343 antikoerper, dJ526I14.2 antikoerper, RGD1305319 antikoerper, BC055368 antikoerper, D430005B17 antikoerper, tubulin tyrosine ligase-like family, member 12 antikoerper, tubulin tyrosine ligase like 12 antikoerper, Tubulin--tyrosine ligase-like protein 12 antikoerper, ttll12 antikoerper, TTLL12 antikoerper, ttll-12 antikoerper, Ttll12 antikoerper

Hintergrund: Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3. Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.,TTLL12,dJ526I14.2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,TTLL12

Molekulargewicht: 74kDa

Gen-ID: 23170

UniProt: Q14166