TMEM100 Antikörper (C-Term)

Produktnummer ABIN7270950

Produktdetails anti-TMEM100 Antikörper

Target: TMEM100 (Transmembrane Protein 100 (TMEM100))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM100 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: TMEM100 Rabbit pAb

Sequenz: ELSCYRCIIP FAVVVFIAGI VVTAVAYSFN SHGSIISIFG LVVLSSGLFL LASSALCWKV RQRSKKAKRR ESQTALVANQ RSLFA

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TMEM100

Target: TMEM100 (Transmembrane Protein 100 (TMEM100))

Andere Bezeichnung: TMEM100 (TMEM100 Produkte)

Synonyme: 1810057C19Rik antikoerper, AV011897 antikoerper, transmembrane protein 100 antikoerper, TMEM100 antikoerper, Tmem100 antikoerper

Hintergrund: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.,TMEM100,TMEM100

Molekulargewicht: 14kDa

Gen-ID: 55273

UniProt: Q9NV29