MGC80584 antikoerper, TAF6L antikoerper, 2810417N14Rik antikoerper, BB223262 antikoerper, C530024J06Rik antikoerper, Paf65a antikoerper, PAF65A antikoerper, TATA-box binding protein associated factor 6 like S homeolog antikoerper, TATA-box binding protein associated factor 6 like antikoerper, taf6l.S antikoerper, TAF6L antikoerper, Taf6l antikoerper
Hintergrund
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.,TAF6L,PAF65A,Epigenetics & Nuclear Signaling,TAF6L