TCIRG1 Antikörper (AA 1-130)

Produktnummer ABIN7270707

Produktdetails anti-TCIRG1 Antikörper

Target: TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))

Bindungsspezifität: AA 1-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCIRG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Verwendungszweck: TCIRG1 Rabbit pAb

Sequenz: MGSMFRSEEV ALVQLFLPTA AAYTCVSRLG ELGLVEFRDL NASVSAFQRR FVVDVRRCEE LEKTFTFLQE EVRRAGLVLP PPKGRLPAPP PRDLLRIQEE TERLAQELRD VRGNQQALRA QLHQLQLHAA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human TCIRG1 (NP_006010.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TCIRG1

Target: TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))

Andere Bezeichnung: TCIRG1 (TCIRG1 Produkte)

Synonyme: OC116 antikoerper, TIRC7 antikoerper, ATP6N1C antikoerper, ATP6a3 antikoerper, Atp6i antikoerper, OC-116 antikoerper, OPTB1 antikoerper, Stv1 antikoerper, Vph1 antikoerper, oc antikoerper, ATP6V0A3 antikoerper, OC-116kDa antikoerper, a3 antikoerper, T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 antikoerper, T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 antikoerper, T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3 antikoerper, Tcirg1 antikoerper, TCIRG1 antikoerper

Hintergrund: This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.,TCIRG1,ATP6N1C,ATP6V0A3,Atp6i,OC-116 kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3,Signal Transduction,Endocrine & Metabolism,TCIRG1

Molekulargewicht: 68kDa/92kDa

Gen-ID: 10312

UniProt: Q13488

Pathways: Transition Metal Ion Homeostasis, Proton Transport