Neuroserpin Antikörper (AA 181-410)

Produktnummer ABIN7270251

Produktdetails anti-Neuroserpin Antikörper

Target: Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))

Bindungsspezifität: AA 181-410

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuroserpin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: SERPINI1 Rabbit pAb

Sequenz: INAVYFKGNW KSQFRPENTR TFSFTKDDES EVQIPMMYQQ GEFYYGEFSD GSNEAGGIYQ VLEIPYEGDE ISMMLVLSRQ EVPLATLEPL VKAQLVEEWA NSVKKQKVEV YLPRFTVEQE IDLKDVLKAL GITEIFIKDA NLTGLSDNKE IFLSKAIHKS FLEVNEEGSE AAAVSGMIAI SRMAVLYPQV IVDHPFFFLI RNRRTGTILF MGRVMHPETM NTSGHDFEEL

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 181-410 of human SERPINI1 (NP_005016.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Neuroserpin

Target: Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))

Andere Bezeichnung: SERPINI1 (SERPINI1 Produkte)

Synonyme: PI12 antikoerper, neuroserpin antikoerper, AI837402 antikoerper, Ns antikoerper, PI-12 antikoerper, Spi17 antikoerper, CG9453 antikoerper, Dmel\\CG9453 antikoerper, Serp2 antikoerper, Sp4 antikoerper, Spn4 antikoerper, Spn4A antikoerper, dSerp2 antikoerper, sp4 antikoerper, spn4 antikoerper, raPIT5a antikoerper, SERPINI1 antikoerper, pi12 antikoerper, serpini1l antikoerper, si:ch211-167c22.4 antikoerper, serpin family I member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade I, member 1 antikoerper, Serpin 42Da antikoerper, serpin peptidase inhibitor, clade I (neuroserpin), member 1 antikoerper, serpin family I member 1 L homeolog antikoerper, SERPINI1 antikoerper, Serpini1 antikoerper, Spn42Da antikoerper, serpini1 antikoerper, serpini1.L antikoerper

Hintergrund: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.,SERPINI1,PI12,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Neuron marker,Growth Cone,SERPINI1

Molekulargewicht: 46kDa

Gen-ID: 5274

UniProt: Q99574

Pathways: Regulation of Hormone Metabolic Process