PTPRK Antikörper (AA 600-750)

Produktnummer ABIN7269702

Produktdetails anti-PTPRK Antikörper

Target: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Bindungsspezifität: AA 600-750

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PTPRK Rabbit pAb

Sequenz: EGVDASLNET ATTITVLLRP AQAKGAPISA YQIVVEELHP HRTKREAGAM ECYQVPVTYQ NAMSGGAPYY FAAELPPGNL PEPAPFTVGD NRTYQGFWNP PLAPRKGYNI YFQAMSSVEK ETKTQCVRIA TKAAATEEPE VIPDPAKQTD R

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-750 of human PTPRK (NP_001129120.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPRK

Target: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Andere Bezeichnung: PTPRK (PTPRK Produkte)

Synonyme: R-PTP-kappa antikoerper, Rptpk antikoerper, AI853699 antikoerper, PTPk antikoerper, RPTPkappa antikoerper, protein tyrosine phosphatase, receptor type K antikoerper, protein tyrosine phosphatase, receptor type, K antikoerper, PTPRK antikoerper, Ptprk antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.,PTPRK,R-PTP-kappa,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PTPRK

Molekulargewicht: 162kDa/163kDa/164kDa

Gen-ID: 5796

UniProt: Q15262

Pathways: Cell-Cell Junction Organization